Boris Karadimchev's first original song was created in 1962 and recorded by popular Bulgarian pop singer Emil Dimitrov. Karadimchev was among the leading composers who supported the beat bands emerging in Bulgaria at the end of the 1960s, such as Shturcite (The Crickets) and Srebarnite Grivni (The Silver Bracelets). 

His song Byala Tishina (White Silence), with lyrics by Bogomil Gudev, performed by Georgi Minchev and Shturcite band won first prize at the Golden Orpheus song festival in 1967 and became an everlasting Bulgarian hit.

Among the singers for whom he wrote are Margret Nikolova, Boyan Ivanov, Boris Gudjunov, Maria Neykova, Bogdana Karadocheva, Margarita Hranova, and his collaborations with rock groups like Factor and Tangra produced true masterpieces in the style of melodic rock. In an interview for cinefish.bg, Boris Karadimchev shared that his serious path in cinema began with an invitation from film director Lyudmil Kirkov to write the music for the 1968 film The Swedish Kings. Before that, Karadimchev had worked only with Zako Heskiya on The Beginning of a Vacation. After two more joint films -  Armando and Don’t Look Back - came one of the most sincere and delicate works in Bulgarian cinema: The Boy Goes Away.

Its clean and natural imagery, romantic atmosphere, Georgi Mishev’s masterful script, the touching performance of lead actor Filip Trifonov, and Karadimchev’s skillful score turned the film into a cult classic for generations of viewers.

“It stayed in the studio. It fit like a beautiful garment, tailored for that film, where those wonderful actors play - may they all rest in peace. The film is amazing! People love it - elegant, refined, intelligent. It had a different atmosphere, very unusual… Every time this song plays, I have felt - inside myself - as if I’m lifting off. There is something very pure in it, very childlike, very romantic. And that carries over to the audience… This song brings a kind of harmony, balance, a special, cleansing feeling. For me it’s a happiness and a huge fortune that it was me who got to sing it, together with a wonderful performer whom I miss greatly - Borko Gudjunov… And thank you to Boris Karadimchev. I consider it one of the emblems of my repertoire.”